Thank you for your reply! I did some demo’ing the past days for many hours, and have tried the ones you recommended. I chose the Gianni from Signature and am quite happy with it. My next step was choosing a head, after reading and watching videos I got the Jackson head from Catwa, also verry nice! But now the hard part; making the both of them match. I spent quite some time playing with the RGB value of the body to make it match the head colour, but I can not find the correct match. I even started to try skins that might work better for the head but it just wont work. I tried it with neck fix from the body aswel the fox from the head. Maybe you can advise me a good matching skin for the head. I am turning into a hermit trying skins and fiddeling with colours. Once again: many thanks in advance.
The enzyme 17α-hydroxylase (CYP 17) is not present in the outer layer of the cortex and, thus, cortisol and androgens cannot be formed in this layer. Steroids and their metabolic by-products (notably lipid hydroperoxides) are released into the adrenal circulation and inhibit critical enzymes in subsequent layers through which the blood flows. As a result, no aldosterone can be synthesized by cells below the outer glomerulosa layer. In the inner layer, 17α-hydroxyprogesterone cannot be converted to cortisol but is shunted into the formation of androgens. Interestingly high cortisol concentrations reaching the adrenal medulla stimulate the synthesis of phenylethanolamine- N -methyltransferase which catalyzes the conversion of norepinephrine to epinephrine (see Box ). Thus, the structural relationship between the cortex and medulla and its blood supply has additional functional implications within the medulla.