Oral equivalent to unasyn

Data from a controlled clinical trial conducted in pediatric patients provided evidence supporting the safety and efficacy of UNASYN for the treatment of skin and skin structure infections. Of 99 pediatric patients evaluable for clinical efficacy, 60 patients received a regimen containing intravenous UNASYN, and 39 patients received a regimen containing intravenous cefuroxime . This trial demonstrated similar outcomes (assessed at an appropriate interval after discontinuation of all antimicrobial therapy) for UNASYN- and cefuroxime-treated patients:

Although patients with acute pyelonephritis traditionally have been hospitalized and treated with intravenous antibiotics, outpatient oral therapy is successful in 90 percent of selected patients with uncomplicated acute pyelonephritis who can tolerate oral intake, will be compliant with the treatment regimen, will return for early follow-up, and have adequate social support 27 , 28 ( Figure 2 ) . Patients with complicated acute pyelonephritis who are more ill or have not responded to outpatient therapy should be hospitalized. Using specific hospitalization criteria ( Table 4 ) , 1 up to 70 percent of patients can be selected for outpatient management. Another option is initial therapy with parenteral antibiotics in an inpatient observation unit, followed by oral therapy as an outpatient. 26 , 29

                                 
                                   Fig. 1                                                    Fig. 2
 

Oral equivalent to unasyn

oral equivalent to unasyn

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oral equivalent to unasyn

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