Steroid premedication for taxol

Perioperatively drugs used to treat asthma should be continued, sometimes in a different format (see table).  Patients taking more than 10mg of  prednisolone daily will require steroid supplementation perioperatively, and may require IV maintenance doses until absorbing drugs. 

Perioperative recommendations for asthma medications      
Class of drug Examples Perioperative recommendation  Notes ß2 agonists  Salbutamol, terbutaline, salmeterol  Convert to nebulised form High doses may lower K + . Causes tachycardia and tremor Anticholinergic drugs 
Ipratropium 
Convert to nebulised form    Inhaled steroids 
Beclomethasone, budesonide, fluticasone  Continue inhaled formulation 
If patient on >1500 mcg/day of beclomethasone, adrenal suppression may be present  
Oral steroids   
Prednisolone Continue as IV hydrocortisone until taking orally (1 mg prednisolone equivalent to 5 mg hydrocortisone) 
If >10 mg/day, adrenal suppression likely Leukotriene inhibitor (anti-inflammatory effect) 
Montelukast, zafirlukast 
Restart when taking oral medications    Mast cell stabilizer 
Disodium cromoglycate 
Continue by inhaler    Phosphodiesterase inhibitor 
Aminophylline 
Continue where possible  Effectiveness in asthma debated. In severe asthma consider converting to an infusion perioperatively (checking levels 12-hrly)

Andreoli, . et al. (1997): Cecil Essentials of Medicine; (4-th ed.)- Company,.
Fauci, . et al. (1998): Harrison’s principles of internal medicine; (14-th ed.)-The McGraw-Hill Companies INC.,.
Shiau, ., Toren, . (2006): The Toronto Notes 2006: Comprehensive Medical References, 26-nd Ed., Canada.
Tierney, . (1997): Pocket guide to the essentials of diagnosis and treatment; (1-th ed.)- Lange medical book, .
Younger-Lewis,C.; Complete home medical guide;Canadian Medical Association (1-st ed.), Dk Publishing Inc.

The 4 mg/mL injection strength may be used for intralesional and soft tissue administration. Doses range from mg to 4 mg injected as a single dose at the appropriate site. For soft tissue and bursal injections a dose of 2 to 4 mg is recommended. Ganglia require a dose of 1 to 2 mg. A dose of to 1 mg is used for injection into tendon sheaths. Usually employed when condition to be treated is limited to 1 or 2 sites. Dosage dependent upon degree of inflammation, size, disease state, and location of affected area. Repeat doses may be given from once every 3 to 5 days to once every 2 to 3 weeks.

Depending on your personal medical history, you may still be a candidate for premedication. For example, antibiotic prophylaxis might be useful for patients undergoing dental procedures who also have compromised immune systems (due to, for instance, diabetes, rheumatoid arthritis, cancer, chemotherapy, and chronic steroid use), which increases the risk of orthopedic implant infection. It may also benefit others with heart conditions . Always talk with your dentist or physician about whether antibiotic prophylaxis before dental treatment is right for you.

Steroid premedication for taxol

steroid premedication for taxol

Depending on your personal medical history, you may still be a candidate for premedication. For example, antibiotic prophylaxis might be useful for patients undergoing dental procedures who also have compromised immune systems (due to, for instance, diabetes, rheumatoid arthritis, cancer, chemotherapy, and chronic steroid use), which increases the risk of orthopedic implant infection. It may also benefit others with heart conditions . Always talk with your dentist or physician about whether antibiotic prophylaxis before dental treatment is right for you.

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