Steroids for croup

There is little in the literature to support recommendations for the use of steroids and vasoconstrictors in the treatment of postintubation croup. We developed a ferret model to study this condition. Ninety-eight ferrets were used in these experiments, which were undertaken to evaluate the efficacy of steroids and/or a long-acting vasoconstrictor, to develop dose-response curves for dexamethasone sodium phosphate if it proved efficacious, and to evaluate the possible synergistic effects of combination therapy. With this animal model, we were able to document a statistically significant early effect of dexamethasone sodium phosphate, but only when administered in large doses (greater than mg/kg). Our data also support the tapering of these large doses within a 20-hour period. The long-acting vasoconstrictor oxymetazoline hydrochloride has a clear and statistically significant beneficial effect that is apparent by 20 hours and continues through 40 hours. We did not find any additive or synergistic effect of the combination of dexamethasone and oxymetazoline. Further studies are underway in our laboratory to elucidate other aspects of this interesting syndrome.

What will they do for you in the ER? As they evaluate your child, they should encourage you to hold him in your lap, remember to keep him calm. They might measure his blood oxygen level, with an oximeter or “pulse-ox.” This uses a small light source that is wrapped around a finger or toe and helps determine how your child is breathing. They might have you blow cool mist in front of your child’s face. If your child’s croup is severe enough (which is why you’re in the ER), they may give him vaporized Epinephrine to breathe with the cool mist. This works quickly to open the airways. Depending on the situation, the ER physician may recommend a short course of steroids. Don’t worry; this is not the “body-building” type of steroids. These will help keep the air passages open over the next few hours to days. Your child will only be on the steroids for a few days, there are no side effects to worry about when used for this short time. The first dose often needs to be given as an injection, since the child with severe breathing difficulty is in no mood to take an oral medication, or he may throw it up.

The maximum dose prescribed under a doctor's care is g daily. Otherwise, the over-the-counter (OTC) maximum daily dose is g daily. Dosage depends upon the age, weight, and any current medical conditions of the patient. Several drugs interact with ibuprofen so check with your doctor, pharmacist, or other health care professional with questions in regard to this drug. Doctors don't know if it is safe to take ibuprofen if your are pregnant, therefore it is not recommended if you are pregnant. According to the American Academy of Pediatrics, ibuprofen is safe to take while breastfeeding.

REFERENCE: FDA Prescribing Information.

The use of antibiotics and short-acting beta-2-agonist bronchodilators in children with typical croup are rarely indicated because of the low incidence of bacterial infection (<1:1000 cases of croup) as well as for physiological reasons. An otorhinolaryngology (ORL) consultation for airway evaluation is indicated when croup symptoms are persistently severe despite treatment. Outpatient referral to ORL is recommended for children with multiple croup episodes and for those who present outside the usual age group for typical croup ( Figure 1 ).

Steroids for croup

steroids for croup

The use of antibiotics and short-acting beta-2-agonist bronchodilators in children with typical croup are rarely indicated because of the low incidence of bacterial infection (<1:1000 cases of croup) as well as for physiological reasons. An otorhinolaryngology (ORL) consultation for airway evaluation is indicated when croup symptoms are persistently severe despite treatment. Outpatient referral to ORL is recommended for children with multiple croup episodes and for those who present outside the usual age group for typical croup ( Figure 1 ).

Media:

steroids for croupsteroids for croupsteroids for croupsteroids for croupsteroids for croup

http://buy-steroids.org