Many adverse effects of licorice poisoning can be seen and most are attributed to the mineralocorticoid effects of GZA. Depending on the dose and intake of licorice, serious problems and even hospitalization can arise. People with previously existing heart or kidney problems may be more susceptible to GZA and licorice poisoning.  It is important to monitor the amount of licorice consumed in order to prevent toxicity. It is difficult to determine a safe level, due to many varying factors from person to person. In the most sensitive individuals, daily intake of about 100 mg GZA can cause problems.  This is equivalent to 50 g licorice sweets. However, in most people, they can consume up to 400 mg before experiencing symptoms, which would be about 200 g licorice sweets. A rule of thumb says a normal healthy person can consume 10 mg GZA a day. 
In Southeast Asia the flower is used as a natural food colouring. In Malay cooking, an aqueous extract is used to colour glutinous rice for kuih ketan (also known as pulut tai tai or pulut tekan in Peranakan /Nyonya cooking) and in nyonya chang . In Kelantan , east part of Malaysia, by adding a few buds of this flower in a pot while cooking white rice will add bluish tint on the rice which is served with other side dishes and such meal is called nasi kerabu . In Thailand, a syrupy blue drink is made called nam dok anchan (น้ำดอกอัญชัน), it is sometimes consumed with a drop of sweet lime juice to increase acidity and turn the juice into pink-purple. In Burmese and Thai cuisines , the flowers are also dipped in batter and fried. Butterfly pea flower tea is made from the ternatea flowers and dried lemongrass and changes color depending on what is added to the liquid, with lemon juice turning it purple. 
In large doses, Blessed Thistle acts as a strong emetic, producing vomiting with little pain and inconvenience. Cold infusions in smaller draughts are valuable in weak and debilitated conditions of the stomach, and as a tonic, creating appetite and preventing sickness. The warm infusion - 1 OZ. of the dried herb to a pint of boiling water - in doses of a wine glassful, forms in intermittent fevers one of the most useful diaphoretics to which employment can be given. The plant was at one time supposed to possess very great virtues against fevers of all kinds.